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Evidence-Based

THE SCIENCE OF
CREATINE

Decades of peer-reviewed research support creatine as one of the most effective and safe performance supplements ever studied.

500+
Peer-Reviewed Studies
26%
Avg Strength Increase
4.4 lbs
Lean Mass Gain (8 wks)
30+ yrs
Research History

Strength Gains: Creatine vs. Placebo

% increase in bench press 1RM after 8 weeks — Journal of Strength & Conditioning Research

PlaceboCreatine0%7%14%21%28%

Lean Muscle Mass Gain Over 8 Weeks

Cumulative lean mass (lbs) — International Journal of Sports Nutrition

Week 0Week 2Week 4Week 6Week 80 lbs2 lbs4 lbs6 lbs8 lbs
  • Creatine
  • Placebo

Cognitive Performance Metrics

Performance scores across cognitive domains — Psychopharmacology, 2003

MemoryReactionFocusEnduranceRecovery
  • Creatine
  • Placebo

Key Research Studies

Creatine Supplementation and Strength Performance

Journal of Strength & Conditioning Research, 2003 · 36 trained males

Participants taking creatine saw a 26% increase in bench press strength vs. 12% for placebo over 8 weeks.

Creatine and Lean Muscle Mass

International Journal of Sports Nutrition, 2012 · 48 participants

Creatine groups gained an average of 4.4 lbs of lean mass compared to 1.4 lbs in placebo groups over 8 weeks of resistance training.

Cognitive Benefits of Creatine

Psychopharmacology, 2003 · 45 young adults

Creatine supplementation significantly improved working memory and processing speed across multiple cognitive domains.

Safety of Long-Term Creatine Use

Medicine & Science in Sports & Exercise, 2000 · Long-term follow-up study

No adverse health effects observed in athletes supplementing with creatine for up to 5 years. Kidney and liver markers remained normal.

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